59-521. Special Topics in Analytical Chemistry
(Prerequisite: 59-321.) (2 lecture hours a week.)
59-531. Special Topics In Organic Chemistry
Topics may include polymer chemistry, natural product chemistry, physical organic chemistry, or design and execution of organic syntheses. (Prerequisite: 59-331 or consent of instructor.) (2 lecture hours a week.)
59-535. Advanced Organic Chemistry
Physical organic chemistry. Includes molecular orbital theory, stereochemistry, thermodynamics, and reaction mechanisms. (Prerequisite: consent of instructor.) (2 lecture hours a week.)
59-541. Statistical Thermodynamics
Development of statistical thermodynamics and its application to theories of gases, condensed states, and chemical equilibria. (2 lecture hours a week.)
59-542. Fourier Transform Nuclear Magnetic Resonance Spectroscopy
Theory and applications of FT NMR in chemical problems, special techniques such as T1, T2 measurements, cross polarization, “magic angle” spinning, 2D spectroscopy, DEPT pulse sequences, and others will be covered. (2 lecture hours a week.)
59-545. Special Topics in Physical Chemistry
(2 lecture hours a week.)
59-546. Advanced Topics in Spectroscopy
Electronic and vibrational spectroscopy of gases, liquids, and solids. Theory and practice of infrared and Raman spectroscopy. Theory and applications of electron spin resonance spectroscopy. (2 lecture hours a week.)
59-550. Applications of Group Theory
Various applications of group theory to the study of organic, inorganic, and organometallic systems. (3 lecture hours a week.)
59-552. Topics in Inorganic Chemistry and Organometallic Chemistry
Topics to be arranged by the instructor, based primarily upon new developments in the field as illustrated by the current research interests of the faculty, as well as by a study of the current literature. (2 lecture hours a week.)
59-553. X-ray Crystallography
Theoretical and experimental aspects of single crystal X-ray diffraction methods for the determination of molecular structures. (2 lecture hours a week.)
59-564. DNA Science and Diagnostics
An advanced lecture and laboratory course dealing with DNA science and the application of DNA technology in the understanding and diagnosis of human disease. The lectures cover the biochemistry and expression of DNA and RNA at the molecular level, the theory and practice of recombinant DNA technology and the application of DNA probes in the diagnosis of human disease. The laboratory component involves construction and cloning of a recombinant DNA molecule. (Prerequisites: 59-360, 59-361, and 59-365, or consent of instructor; antirequisite: 59-468.) (2 lecture hours, 1 laboratory hour a week.)
59-565. Membrane Biochemistry
The structure and function of artificial and natural membranes. Special consideration will be given to the identification and function of membrane proteins. (Prerequisites: 59-360 and 59-361 or 59-362 and 59-363, or equivalent.) (2 lecture hours a week.)
59-570. Advanced Quantum Chemistry
Perturbation and variation theories. Theories of many electron atoms and general theories of chemical bonds in diatomic and polyatomic molecules. (Prerequisite: 59-341 or equivalent.) (3 lecture hours a week.)
59-581. Analytical Toxicology
Analysis of drugs and other toxic substances in biological fluids. The metabolism of drugs as well as the symptomology of poisoning of common therapeutic drugs and the more common industrial chemicals will be discussed. (Prerequisites: 59-360 and 59-361 or 59-362 and 59-363, or consent of instructor.) (2 lecture hours a week.)
59-600. Directed Special Studies
A special course of studies with content and direction approved by the student's research advisor and supervisory committee. Although there may be no formal lecture requirements, the course will be equivalent to three one-hour lectures a week for one term. The student will be required (a) to produce a critical review which will be assessed by his or her supervisory committee; the presentation and standard of the review must be appropriate for publication in a scientific journal; (b) to spend one term working in an agreed industrial setting; the quality of work will be assessed by the supervisory committee. This work may be related to but not part of the research undertaken in 59-797 or 59-798. (Prerequisite: approval of the Program Committee.)
The course cannot be repeated for credit under (a) above. Under normal circumstances, M.Sc. students may take this course only once; Ph.D. students may register under (b) above for two terms of this industrial experience.
59-620. Analytical Spectroscopy of Surfaces
Surface spectroscopic techniques and their application to the analysis of chemisorbed and physisorbed species and monomolecular layers. (Prerequisite: 59-321 or equivalent.) (2 lecture hours a week.)
59-630. Synthetic Methods in Organic Chemistry
A study of some important organic reactions with emphasis on their practical application in synthesis. (Prerequisites: 59-330 and 59-331, or consent of instructor.) (2 lecture hours a week.)
59-631. Advanced Topics in Organic Syntheses
The design, execution, and methodology of total syntheses of complex molecules will be discussed. Emphasis will be placed on both retrosynthetic pathways and execution. (Prerequisites: 59-330 and 59-331, or consent of instructor.) (2 lecture hours a week.)
59-633. Current Topics in Organic Chemistry
Topics to be arranged by the instructor, based primarily upon new developments in the field as illustrated by the current research interests of the faculty, as well as by a study of the current literature. (Prerequisites: 59-331 or consent of instructor.) (2 lecture hours a week.)
59-634. Advanced Topics in Organic Chemistry
Special topics in organic chemistry will be described. Some of these may include natural product chemistry, organometallic chemistry or heterocyclic chemistry. (Prerequisite: consent of instructor.) (2 lecture hours a week.)
59-636. Advanced Topics in Physical Organic Chemistry
A survey of structure, mechanism, and theory in organic chemistry. (Prerequisite: consent of instructor.) (2 lecture hours a week.)
59-651. Organometallic Chemistry
A detailed study of selected advanced topics in organometallic chemistry. Typical subjects include (at the discretion of the instructors) main group organometallic chemistry; thermochemical methods in organometallic chemistry; catalysis by organometallics, detailed structural studies. (2 or 3 lecture hours a week.)
59-653. Advanced Topics in Organometallic Chemistry
Topics to be arranged by the instructor, based primarily upon new developments in the field as illustrated by the current research interests of the faculty, as well as by a study of the current literature. (2 lecture hours a week.)
59-655. Selected Topics in Inorganic Chemistry
Spectroscopic applications to inorganic systems. Typical of topics covered from year to year are optical spectroscopy, vibrational spectroscopy and normal coordinate analysis, ESR and NMR spectroscopy, and photoelectron spectroscopy. (2 lecture hours a week.)
59-660. Protein Chemistry I
Protein chemistry; chemical modification, protein folding, post-translational modification, lipoproteins, and glycoproteins. (Prerequisite: 59-365 or equivalent.) (2 lecture hours a week.)
59-661. Protein Chemistry II
Biophysical chemistry; advanced kinetic techniques, pre-steady state, perturbation based methods, review of instrumentation, and examples of how these techniques are currently used to solve biochemical problems. (Prerequisite: 59-660.) (2 lecture hours a week.)
59-663. Special Topics in Biochemistry
(Prerequisites: 59-360 and 59-361, or 59-362 and 59-363, or equivalent.) (2 lecture hours a week.)
59-671. Special Topics in Theoretical Chemistry
Topics to be selected by registrants but will generally be molecular orbital calculations for organic and inorganic chemists. (2 lecture hours a week.)
59-684. Pathophysiology
Introductory course in human pathology with special emphasis on chemical aspects of disease. An examination of the interrelationships and homeostatic control of the major biochemical parameters in health, and the cause and nature of the anomalies of these parameters occurring in disease. A case-oriented approach to the diagnosis of disease based primarily on examination of the biochemical parameters, with the aim not only of identifying the disease, but also of explaining the significance of the pertinent biochemical parameters. (Prerequisites: Biology 55-140 and 55-141, 59-360 or 59-362, or equivalent, and consent of instructor.) (2 lecture hours a week and demonstrations.)
59-686. Advanced Bioanalytical Topics
(Prerequisite: 59-360 or 59-362, or equivalent.) (2 lecture hours a week.)
59-710. The Research Proposal
This course focuses on the development and presentation of a research proposal, as well as the cultivation of a wide base of knowledge of the chemical and biochemical literature. Techniques of research proposal composition, with particular reference to subject area, budgetary considerations, and written and oral presentation techniques will be discussed. The student will be required to develop and defend his or her own research proposal in chemistry and/or biochemistry. The subject of this proposal must not be from the research work undertaken for the Ph.D. thesis. A written proposal will be submitted to the student's advisory committee and will be followed by an oral presentation and defense of the proposal. The advisory committee will evaluate the originality, the significance, the clarity of the written and oral presentation, and the student's knowledge of the area in the defense. (Prerequisite: registration in the Ph.D. program. The oral presentation and proposal defense will take place during the term of registration.)
59-795. Seminar
59-797. Master's Thesis
59-798. Doctoral Dissertation